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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of uveitis
ncRNA name hsa-miR-9-3
ncRNA Category miRNA
Disease name uveitis
Species Homo sapiens
Tissues/Cell_line blood; peripheral blood mononuclear cells (PBMCs); human primary RPE (hRPE) cells
Methods transfection, qRT-PCR, flow cytometry, immunofluorescence staining, luciferase reporter assay, ELISA
Expression pattern low copy numbers
Functional description Low copy numbers of miR-9-3 and miR-143, and high copy numbers of miR-301a, confer risk for AAU+AS+ but not for AAU+AS−.The mechanism of miR-9-3 in AAU+AS+ pathogenesis may involve a response to triggers leading to a lower IL-6 expression.
PubMed ID 28384720
Year 2017
Title miRNA Copy Number Variants Confer Susceptibility to Acute Anterior Uveitis With or Without Ankylosing Spondylitis.
Drug-related ncRNA NO

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